Bottom-Up Structuring and Site-Selective Modification of Hydrogels Using a Two-Photon [2+2] Cycloaddition of Maleimide.
basic_science · Level V
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- Record sourced from PubMed, PMID 27862380.
- Also identified by DOI 10.1002/adma.201603327.
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Abstract
Creating hydrogel systems to mimic the extracellular matrix is often limited by their static nature. The use of a two-photon [2+2] cycloaddition of maleimide groups to structure surfaces, to create hydrogels, and add 3D modifications with sub-micrometer precision is reported. The absence of photoinitiators and usage of near-infrared light is promising for future in vivo studies.