Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel-Based Chemo-Electro Signal Transduction for Molecular Communication.

Liu, Yi; Tsao, Chen-Yu; Kim, Eunkyoung; Tschirhart, Tanya; Terrell, Jessica L; Bentley, William E; Payne, Gregory F · Adv Healthc Mater · 2017

basic_science · Level V

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Abstract

A hydrogel-based dual film coating is electrofabricated for transducing bio-relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox-inactive substrate into a redox-active intermediate, which is detected through an amplification mechanism of the inner redox-capacitor film.

Medical subject headings