Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues.

Ma, Yun-Han; Dou, Wei-Tao; Pan, Yu-Fei; Dong, Li-Wei; Tan, Ye-Xiong; He, Xiao-Peng; Tian, He; Wang, Hong-Yang · Adv Mater · 2017

basic_science · Level V

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Abstract

A 2D peptidosheet unravels CD47 as a potential biomarker to image hepatocarcinoma and cholangiocarcinoma cells and tissues. Supramolecular assembly between water-soluble 2D MoS<sub>2</sub> and a peptide probe produces the 2D peptidosheet suited for the profiling of hepatocarcinoma and cholangiocarcinoma tissues over healthy tissues on clinical specimens.

Medical subject headings