Diastolic Dysfunction and Hypertension.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27884237.
- Also identified by DOI 10.1016/j.mcna.2016.08.013.
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Abstract
Left ventricular (LV) diastolic dysfunction (LVDD) is characterized by alterations in LV diastolic filling, and is a strong predictor of cardiovascular events and heart failure. Hypertension is the most important risk factor for LVDD in the community and promotes LVDD through several mechanisms, including hemodynamic overload and myocardial ischemia. Associated factors such as age, ethnicity, dietary sodium, obesity, diabetes mellitus, and chronic kidney disease also contribute to LVDD in hypertensive individuals. Blood pressure lowering using antihypertensive medications can improve LVDD; however, it remains unclear whether this improvement in LV diastolic function can improve cardiovascular outcomes.
Medical subject headings
- Hypertension
- Ventricular Dysfunction, Left