Commentary for "human kidney pericytes produce renin".

Kurtz, Armin · Kidney Int · 2016

editorial · Level V

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Abstract

Renin-secreting cells of the kidney display several particularities, including their intrarenal localization in the fetal and in the adult kidney, their ultrastructure, and the mode by which they secrete renin into circulation to trigger the activity of the renin-angiotensin-aldosterone system. The cell type from which renin cells differentiate has long been subject to speculation. The paper by Stefanska et al. now strongly suggests that renin cells are or derive from pericytes.

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