Lymphadenectomy for Treatment of Early-Stage Endometrial Cancer.

Frost, Jonathan A; Webster, Katie E; Morrison, Jo · JAMA Oncol · 2017

meta_analysis · Level I

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Abstract

What is the association between lymphadenectomy and survival, disease recurrence, and surgical morbidity in women with presumed early-stage, low-grade endometrial carcinoma? The evidence from randomized clinical trials suggests that lymphadenectomy does not improve survival or decrease disease recurrence in women with early-stage, low-grade endometrial carcinoma. Furthermore lymphadenectomy is associated with an increase in both short- and long-term surgery-related systemic morbidity.

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