Stem cells and interspecies chimaeras.
basic_science · Level V
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- Record sourced from PubMed, PMID 27905428.
- Also identified by DOI 10.1038/nature20573.
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Abstract
Chimaeras are both monsters of the ancient imagination and a long-established research tool. Recent advances, particularly those dealing with the identification and generation of various kinds of stem cells, have broadened the repertoire and utility of mammalian interspecies chimaeras and carved out new paths towards understanding fundamental biology as well as potential clinical applications.