The Mediator of Hematopoietic Stem Cell Homeostasis.
editorial · Level V
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- Record sourced from PubMed, PMID 27912086.
- Also identified by DOI 10.1016/j.stem.2016.11.012 and PMC identifier 6547814.
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Abstract
Mechanisms establishing and maintaining promoter-enhancer interactions in hematopoietic stem cells (HSCs) to maintain stem cell identity are not fully understood. In this issue of Cell Stem Cell, Aranda-Orgilles et al. (2016) describe a role for a member of the Mediator complex in maintaining HSC-specific enhancers and hematopoietic homeostasis.
Medical subject headings
- Hematopoietic Stem Cells
- Homeostasis