Stimuli-Responsive DNA-Functionalized Metal-Organic Frameworks (MOFs).

Kahn, Jason S; Freage, Lina; Enkin, Natalie; Garcia, Miguel Angel Aleman; Willner, Itamar · Adv Mater · 2017

basic_science · Level V

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Abstract

The synthesis of nucleic acid-functionalized metal-organic frameworks (MOFs) is described. The metal-organic frameworks are loaded with a dye being locked in the structures by means of stimuli-responsive nucleic acid caps. The pH and K<sup>+</sup> -ion-triggered release, and switchable release, are demonstrated.

Medical subject headings