Metal-Organic Framework as a Protective Coating for Biodiagnostic Chips.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27925296.
- Also identified by DOI 10.1002/adma.201604433 and PMC identifier 5369648.
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Abstract
Zeolitic imidazolate framework-8 (ZIF-8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF-8-protected biochip can be restored by a simple water-rinsing step, making it highly convenient for use in point-of-care and resource-limited settings.
Medical subject headings
- Metal-Organic Frameworks