Quantification of Type, Timing, and Extent of Cell Body and Nucleus Deformations Caused by the Dimensions and Hydrophilicity of Square Prism Micropillars.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27925459.
- Also identified by DOI 10.1002/adhm.201600857.
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Abstract
Novel digital analysis strategies are developed for the quantification of changes in the cytoskeletal and nuclear morphologies of mesenchymal stem cells cultured on micropillars. Severe deformations of nucleus and distinct conformational changes of cell body ranging from extensive elongation to branching are visualized and quantified. These deformations are caused mainly by the dimensions and hydrophilicity of the micropillars.
Medical subject headings
- Cell Body
- Cell Nucleus
- Cytoskeleton