Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 27965302.
- Also identified by DOI 10.1093/cid/ciw743.
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Abstract
In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).
Medical subject headings
- Carrier State
- Enterobacteriaceae
- Enterobacteriaceae Infections
- Proton Pump Inhibitors
- Rectum
- beta-Lactamases