Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson's disease.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 27966027.
- Also identified by DOI 10.1007/s00701-016-3044-5.
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Abstract
Deep brain stimulation (DBS) in the thalamic ventral intermediate (Vim) or the subthalamic nucleus (STN) reportedly improves medication-refractory Parkinson's disease (PD) tremor. However, little is known about the potential synergic effects of combined Vim and STN DBS. We describe a 79-year-old man with medication-refractory tremor-dominant PD. Bilateral Vim DBS electrode implantation produced insufficient improvement. Therefore, the patient underwent additional unilateral left-sided STN DBS. Whereas Vim or STN stimulation alone led to partial improvement, persisting tremor resolution occurred after simultaneous stimulation. The combination of both targets may have a synergic effect and is an alternative option in suitable cases.
Medical subject headings
- Deep Brain Stimulation
- Parkinson Disease
- Subthalamic Nucleus
- Tremor
- Ventral Thalamic Nuclei