Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques.
Level V
Where this comes from
- Record sourced from PubMed, PMID 27974178.
- Also identified by DOI 10.1016/j.cmet.2016.11.013.
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Abstract
Age dominates as a risk factor for human atherosclerosis, yet the underlying mechanisms remain elusive. A recent report described accumulation of senescent cells in atheromata of hypercholesterolemic mice and provides novel insights into how genes expressed by aging cells associate with the characteristics of human plaques implicated in cardiovascular events.
Medical subject headings
- Macrophages
- Plaque, Atherosclerotic