Stem cells: Valine starvation leads to a hungry niche.
basic_science · Level V
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- Record sourced from PubMed, PMID 27974805.
- Also identified by DOI 10.1038/nature21106 and PMC identifier PMC4325197.
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Abstract
The haematopoietic stem cells that rejuvenate blood depend on a dietary source of the amino acid valine — a finding that has been exploited to reduce the toxicity of bone-marrow transplantation in mice.