Public variant databases: liability?
Where this comes from
- Record sourced from PubMed, PMID 27977006.
- Also identified by DOI 10.1038/gim.2016.189 and PMC identifier 5527130.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing.Genet Med advance online publication 15 December 2016.
Medical subject headings
- Databases, Genetic
- Databases, Nucleic Acid