Bursts of Reprogramming: A Path to Extend Lifespan?

Mahmoudi, Salah; Brunet, Anne · Cell · 2016

basic_science · Level V

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Abstract

In a thought-provoking study, Ocampo et al. show that the cyclic expression of stem cell reprogramming factors in vivo increases the lifespan of a mouse model of premature aging and provides health benefits to chronologically old, normal mice.

Medical subject headings