Easy Stress Relief by EZH2.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27984719.
- Also identified by DOI 10.1016/j.cell.2016.11.051.
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Abstract
While we are beginning to appreciate the cellular roles played by long noncoding RNAs, the function of transcripts emerging from repetitive genomic regions remains enigmatic. In this issue, Zovoilis et al. report that the polycomb protein EZH2, upon heat shock, facilitates transcription of stress-responsive genes by inducing the degradation of the transcriptional repressor B2 repeat RNA.
Medical subject headings
- Polycomb-Group Proteins
- RNA, Long Noncoding