ReconMap: an interactive visualization of human metabolism.

Noronha, Alberto; Daníelsdóttir, Anna Dröfn; Gawron, Piotr; Jóhannsson, Freyr; Jónsdóttir, Soffía; Jarlsson, Sindri; Gunnarsson, Jón Pétur; Brynjólfsson, Sigurður et al. · Bioinformatics · 2017

basic_science · Level V

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Abstract

A genome-scale reconstruction of human metabolism, Recon 2, is available but no interface exists to interactively visualize its content integrated with omics data and simulation results. We manually drew a comprehensive map, ReconMap 2.0, that is consistent with the content of Recon 2. We present it within a web interface that allows content query, visualization of custom datasets and submission of feedback to manual curators. ReconMap can be accessed via http://vmh.uni.lu , with network export in a Systems Biology Graphical Notation compliant format released under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. A Constraint-Based Reconstruction and Analysis (COBRA) Toolbox extension to interact with ReconMap is available via https://github.com/opencobra/cobratoolbox . ronan.mt.fleming@gmail.com.

Medical subject headings