Early Clinical Response as a Predictor of Late Treatment Success in Patients With Acute Bacterial Skin and Skin Structure Infections: Retrospective Analysis of 2 Randomized Controlled Trials.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 28003218.
- Also identified by DOI 10.1093/cid/ciw750.
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Abstract
In the treatment of acute bacterial skin and skin structure infections, pooled data from 2 clinical trials (N = 1333 patients) showed that programmatic and investigator-assessed early treatment success both had a high positive predictive value (94.3%-100.0%) for late clinical cure, including among hospitalized patients. The negative predictive value of programmatic early success was <20%. These exploratory findings require prospective real-world evaluation. NCT01170221; NCT01421511.
Medical subject headings
- Anti-Bacterial Agents
- Skin Diseases, Bacterial