Comment on "A small-molecule antivirulence agent for treating Clostridium difficile infection".

Beilhartz, Greg L; Tam, John; Zhang, Zhifen; Melnyk, Roman A · Sci Transl Med · 2016

expert_opinion · Level V

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Abstract

New insights into the mechanism of action of ebselen, a small-molecule antivirulence agent that reduces disease pathology in a mouse model of Clostridium difficile infection, suggest a different molecular target may be responsible for its efficacy.

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