MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28011775.
- Also identified by DOI 10.1093/bioinformatics/btw697 and PMC identifier 5408820.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/. m.dumas@imperial.ac.uk . Supplementary data are available at Bioinformatics online.
Medical subject headings
- Computational Biology
- Metabolic Networks and Pathways
- Signal Transduction
- Software