Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28026126.
- Also identified by DOI 10.1002/adhm.201601095 and PMC identifier 5469035.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A fiber composite system is presented which recapitulates the fiber-composite-like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransduction research, providing a platform with physiologically relevant conditions for investigating cell behavior in different tissue types.
Medical subject headings
- Biomimetic Materials
- Hydrogels
- Mechanotransduction, Cellular
- Shear Strength
- Tendons