Light-Enhancing Plasmonic-Nanopore Biosensor for Superior Single-Molecule Detection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28026129.
- Also identified by DOI 10.1002/adma.201605442.
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Abstract
A stacked plasmonic nanowell-nanopore biosensor strongly suppresses the background fluorescence from the bulk and yields net more than tenfold enhancement of the fluorescence intensity. The device offers extremely high signal-to-background (S/B) ratio for single-molecule detection at ultralow excitation laser intensities, while maintaining extremely high temporal bandwidth for single-DNA sensing.
Medical subject headings
- Nanopores