dAPE: a web server to detect homorepeats and follow their evolution.
Where this comes from
- Record sourced from PubMed, PMID 28031183.
- Also identified by DOI 10.1093/bioinformatics/btw790 and PMC identifier 5408840.
- Licence recorded as CC BY-NC.
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Abstract
Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats. dAPE can be accessed from http://cbdm-01.zdv.uni-mainz.de/∼munoz/polyx . munoz@uni-mainz.de. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Evolution, Molecular
- Repetitive Sequences, Amino Acid
- Software