Implementation of a Rapid Genotypic Assay to Promote Targeted Ciprofloxacin Therapy of Neisseria gonorrhoeae in a Large Health System.

Allan-Blitz, Lao-Tzu; Humphries, Romney M; Hemarajata, Peera; Bhatti, Ashima; Pandori, Mark W; Siedner, Mark J; Klausner, Jeffrey D · Clin Infect Dis · 2017

other · Level V

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Abstract

Multidrug-resistant Neisseria gonorrhoeae is a top threat to public health. In November 2015, UCLA Health introduced a rapid gyrase A (gyrA) genotypic assay for prediction of Neisseria gonorrhoeae susceptibility to ciprofloxacin. We found a significant reduction in ceftriaxone use with a concomitant increase in targeted therapy.

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