Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28061350.
- Also identified by DOI 10.1016/j.stem.2016.12.003.
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Abstract
New methods to manipulate gene and cell state can be used to engineer cell functionality, simplify quality assessment, and enhance manufacturability. These strategies could help overcome unresolved cell therapy manufacturing challenges and complement frameworks to design quality into these complex cellular systems, ultimately increasing patient access to living therapeutics.
Medical subject headings
- Artificial Cells
- Cell- and Tissue-Based Therapy