Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28061353.
- Also identified by DOI 10.1016/j.stem.2016.12.012.
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Abstract
The enteric nervous system (ENS) regulates numerous gastrointestinal functions, including epithelial barrier permeability and motility. In a recent Nature Medicine study, Workman et al. (2016) propose a method for introducing human pluripotent stem cell-derived enteric neural crest cells into developing human intestinal organoids, thereby restoring ENS cell types and contractile function.
Medical subject headings
- Enteric Nervous System
- Organoids