Hacking the Matrix.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28061355.
- Also identified by DOI 10.1016/j.stem.2016.12.010 and PMC identifier 6334287.
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Abstract
Recently in Nature, Gjorevski et al. (2016) describe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro growth of intestinal stem cells and organoids. The hydrogel allows exquisite control over the chemical and physical in vitro niche and enables identification of regulatory properties of the matrix.
Medical subject headings
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Organoids