RECKONER: read error corrector based on KMC.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28062451.
- Also identified by DOI 10.1093/bioinformatics/btw746.
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Abstract
Presence of sequencing errors in data produced by next-generation sequencers affects quality of downstream analyzes. Accuracy of them can be improved by performing error correction of sequencing reads. We introduce a new correction algorithm capable of processing eukaryotic close to 500 Mbp-genome-size, high error-rated data using less than 4 GB of RAM in about 35 min on 16-core computer. Program is freely available at http://sun.aei.polsl.pl/REFRESH/reckoner . sebastian.deorowicz@polsl.pl. Supplementary data are available at Bioinformatics online.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- Software