Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28081298.
- Also identified by DOI 10.1002/adhm.201600549 and PMC identifier 5896558.
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Abstract
In a rat model of right free wall replacement, the transplantation of an engineered multilayered myocardial patch fabricated from a polycaprolactone membrane supporting a chitosan/heart matrix hydrogel induces significant muscular and vascular remodeling and results in a significantly higher right ventricular ejection fraction compared to use of a commercially available pericardium patch.
Medical subject headings
- Chitosan
- Hydrogels
- Materials Testing
- Membranes, Artificial
- Myocardium
- Pericardium