Shining a Light on Phase Separation in the Cell.

Paci, Giulia; Lemke, Edward A · Cell · 2017

basic_science · Level V

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Abstract

Phase separation of proteins is recognized as an important aspect of cellular organization and disease mechanisms. Shin et al. introduce a novel optogenetic tool, which enables different phase-space regimes inside living cells to be assessed and the transition paths between them to be studied with unprecedented spatiotemporal control.

Medical subject headings