SnapShot: Class 2 CRISPR-Cas Systems.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28086097.
- Also identified by DOI 10.1016/j.cell.2016.12.038.
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Abstract
Class 2 CRISPR-Cas systems are characterized by effector modules consisting of single, large, multidomain proteins that appear to have been derived from mobile genetic elements. Some Class 2 effector proteins, such as Cas9 and Cas12a (Cpf1), have been successfully repurposed for genome engineering.
Medical subject headings
- Bacteria
- CRISPR-Cas Systems