Balancing Ethical Pros and Cons of Stem Cell Derived Gametes.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28091967.
- Also identified by DOI 10.1007/s10439-017-1793-9.
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Abstract
In this review we aim to provide an overview of the most important ethical pros and cons of stem cell derived gametes (SCD-gametes), as a contribution to the debate about reproductive tissue engineering. Derivation of gametes from stem cells holds promising applications both for research and for clinical use in assisted reproduction. We explore the ethical issues connected to gametes derived from embryonic stem cells (both patient specific and non-patient specific) as well as those related to gametes derived from induced pluripotent stem cells. The technology of SCD-gametes raises moral concerns of how reproductive autonomy relates to issues of embryo destruction, safety, access, and applications beyond clinical infertility.
Medical subject headings
- Bioethical Issues
- Germ Cells
- Human Embryonic Stem Cells
- Induced Pluripotent Stem Cells
- Infertility
- Reproductive Techniques, Assisted
- Tissue Engineering