ERAD-icating mutant insulin promotes functional insulin secretion.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28100837.
- Also identified by DOI 10.1126/scitranslmed.aal4995.
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Abstract
Overexpression of a chaperone protein liberates functional insulin from a misfolded mutant partner to improve insulin secretion.
Medical subject headings
- Insulin
- Proinsulin