Oncometabolic Tracks in the Heart.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 28104766.
- Also identified by DOI 10.1161/CIRCRESAHA.116.310115 and PMC identifier 6237182.
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Abstract
The term cancer and the heart is readily associated with the cardiotoxicity of antineoplastic agents, such as anthracyclines or receptor tyrosine kinase inhibitors. This <i>Viewpoint</i> offers a different perspective, drawing attention to the consequences of metabolic dysregulation in cancers for energy substrate metabolism and contractile function of the heart and to common cellular strategies present in cancers and in the failing heart.
Medical subject headings
- Energy Metabolism
- Heart
- Myocardium
- Neoplasms