Accelerating the search for the missing proteins in the human proteome.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28117396.
- Also identified by DOI 10.1038/ncomms14271 and PMC identifier 5286205.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins encoded by the human genome. Currently, ∼18% of the proteins in the human proteome (the missing proteins) do not have high-stringency evidence (for example, mass spectrometry) confirming their existence, while much additional information is available about many of these missing proteins. Here, we present MissingProteinPedia as a community resource to accelerate the discovery and understanding of these missing proteins.
Medical subject headings
- Chromosome Mapping
- Databases, Protein
- Proteogenomics
- Proteome