Rational Design of Molecular Fluorophores for Biological Imaging in the NIR-II Window.

Yang, Qinglai; Ma, Zhuoran; Wang, Huasen; Zhou, Bin; Zhu, Shoujun; Zhong, Yeteng; Wang, Junying; Wan, Hao et al. · Adv Mater · 2017

basic_science · Level V

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Abstract

A new design for second near-infrared window (NIR-II) molecular fluorophores based on a shielding unit-donor-acceptor-donor-shielding unit (S-D-A-D-S) structure is reported. With 3,4-ethylenedioxy thiophene as the donor and fluorene as the shielding unit, the best performance fluorophores IR-FE and IR-FEP exhibit an emission quantum yield of 31% in toluene and 2.0% in water, respectively, representing the brightest organic dyes in NIR-II region reported so far.

Medical subject headings