A Step-by-Step Multiple Stimuli-Responsive Nanoplatform for Enhancing Combined Chemo-Photodynamic Therapy.

Wang, Yi; Wei, Guoqing; Zhang, Xiaobin; Xu, Funeng; Xiong, Xiang; Zhou, Shaobing · Adv Mater · 2017

basic_science · Level V

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Abstract

A robust and smart protoporphyrin-based polymer nanoplatform, which is capable of successively recognizing the variation of biological signals and reacting with them in a dynamic mode, is successfully developed. It combines the chemotherapy and photodynamic therapy in a same system, leading to a high treatment outcome while a low adverse side effect of therapeutic agent.