Rabies Virus-Inspired Silica-Coated Gold Nanorods as a Photothermal Therapeutic Platform for Treating Brain Tumors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28134459.
- Also identified by DOI 10.1002/adma.201605563.
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Abstract
Rabies virus-inspired silica-coated gold nanorods are fabricated by mimicking size, shape, surface glycoprotein property and in vivo behavior of the rabies virus. These nanorods not only resemble the appearance of the actual rabies virus but also travel into the brain through the neuronal pathway bypassing the blood-brain barrier, and moreover respond to near-infrared laser (808 nm) irradiation, emit heat, and effectively suppress brain tumors.
Medical subject headings
- Antineoplastic Agents
- Biomimetic Materials
- Brain Neoplasms
- Glioma
- Laser Therapy
- Nanotubes