Strategies for Combating Opioid-Induced Constipation: Targeted Mechanisms to Maintain Pain Control Without Compromise.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28143720.
- Also identified by DOI 10.1016/j.pmrj.2017.01.003.
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Abstract
Opioid-induced constipation (OIC) is a common side effect of opioid use and can occur from the outset of opioid therapy (Online access: http://courses.elseviercme.com/aapmr2016/638e). OIC has been reported to interfere with pain management, increase health care costs, decrease work productivity and daily activities, and significantly affect patient quality of life. It can also lead to bowel obstruction. Assessing and managing OIC is important for establishing maximum function for patients. Several pharmacologic approaches, with different mechanisms of action, are available or in development.
Medical subject headings
- Analgesics, Opioid
- Chronic Pain
- Constipation