Explanatory Style in Patients with Rheumatoid Arthritis: An Unrecognized Predictor of Mortality.

Crowson, Aaron D; Colligan, Robert C; Matteson, Eric L; Davis, John M; Crowson, Cynthia S · J Rheumatol · 2017

case_control · Level III

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Abstract

To determine whether pessimistic explanatory style altered the risk for and mortality of patients with rheumatoid arthritis (RA). The study included subjects from a population-based cohort with incident RA and a non-RA comparison cohort who completed the Minnesota Multiphasic Personality Inventory. Among 148 RA and 135 non-RA subjects, pessimism was associated with development of rheumatoid factor (RF)-positive RA. Pessimism was associated with an increased risk of mortality [HR 2.88 with similar magnitude to RF+ (HR 2.28)]. Pessimistic explanatory style was associated with an increased risk of developing RA and increased mortality rate in patients with RA.

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