Cation Tuning of Supramolecular Gel Properties: A New Paradigm for Sustained Drug Delivery.

Ramin, Michael A; Sindhu, Kotagudda Ranganath; Appavoo, Ananda; Oumzil, Khalid; Grinstaff, Mark W; Chassande, Olivier; Barthélémy, Philippe · Adv Mater · 2017

basic_science · Level V

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Abstract

Hydrogels formed by the self-assembly of low-molecular-weight gelators (LMWGs) are promising scaffolds for drug-delivery applications. A new biocompatible hydrogel, resulting from the self-assembly of nucleotide-lipid salts can be safely injected in vivo. The resulting hydrogel provides sustained-release of protein for more than a week.

Medical subject headings