ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data.
other · Level V
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- Record sourced from PubMed, PMID 28172348.
- Also identified by DOI 10.1093/bioinformatics/btw634.
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Abstract
The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations. ARResT/Interrogate is implemented primarily in R, and is freely available at http://bat.infspire.org/arrest/interrogate/ nikos.darzentas@gmail.com Supplementary data are available at Bioinformatics online.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- Immunogenetics
- Immunoglobulins
- Receptors, Antigen, T-Cell
- Software