Physiology: An atypical switch for metabolism and ageing.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28178230.
- Also identified by DOI 10.1038/nature21500 and PMC identifier PMC4996648.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The enzyme S6K1 enzyme phosphorylates the enzyme glutamyl-prolyl t-RNA synthetase to modulate metabolic activity and lifespan, revealing an atypical role for this synthetase as a target of a key metabolic signalling pathway.