Simulome: a genome sequence and variant simulator.
basic_science · Level V
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- Record sourced from PubMed, PMID 28186240.
- Also identified by DOI 10.1093/bioinformatics/btx091 and PMC identifier 5870732.
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Abstract
Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in combination with real reads generated from next-generation sequencing platforms, or with simulated reads. Simulome is available for download at https://github.com/price0416/Simulome and is free for use under the MIT license.