Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection.

Aravanis, Alexander M; Lee, Mark; Klausner, Richard D · Cell · 2017

review · Level V

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Abstract

Curative therapies are most successful when cancer is diagnosed and treated at an early stage. We advocate that technological advances in next-generation sequencing of circulating, tumor-derived nucleic acids hold promise for addressing the challenge of developing safe and effective cancer screening tests.

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