Glucose-Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid.
basic_science · Level V
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- Record sourced from PubMed, PMID 28195436.
- Also identified by DOI 10.1002/adma.201606380 and PMC identifier 5921932.
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Abstract
Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.