Host Materials Transformable in Tumor Microenvironment for Homing Theranostics.

Yang, Pei-Pei; Luo, Qiang; Qi, Guo-Bin; Gao, Yu-Juan; Li, Bing-Nan; Zhang, Jing-Ping; Wang, Lei; Wang, Hao · Adv Mater · 2017

basic_science · Level V

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Abstract

A pathology-adaptive nanosystem, in which nest-like hosts are built based on nanofibers that are transformed from i.v. injected nanoparticles under the acidic tumor microenvironment. The solid tumor is artificially modified by nest-like hosts readily and firmly, resulting in highly efficient accumulation and stabilization of guest theranostics. This strategy shows great potential for the theranostics delivery to tumors.

Medical subject headings