Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis.

Lamoth, Frederic; Chung, Shimin J; Damonti, Lauro; Alexander, Barbara D · Clin Infect Dis · 2017

retrospective_cohort · Level III

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Abstract

Breakthrough invasive mold infections (IMIs) that occur during posaconazole or voriconazole prophylaxis are rare complications for which epidemiological data are lacking. This retrospective analysis comparing 24 microbiologically documented breakthrough with 66 nonbreakthrough IMIs shows a shift towards non-Aspergillus molds with a significantly increased proportion of rare multidrug-resistant molds.

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